Lipopolyamines of spermine type for construction of liposomal transfection systems

Lukas Drasar and Miroslav Ledvina, from the  Institute of Organic Chemistry and Biochemistry (IOCB Prague), invented in collaboration with Zina Korvasova and Jaroslav Turanek from the Faculty of Veterinary Medicine of the University of Veterinary and Pharmaceutical Science Brno,  new lipopolyamines. The scientists developed and validated the synthesis of those lipopolyamines and their use for construction of polycationic self-assembling drug carriers based on negatively charged fragments of nucleic acids.  The patent application for there invention was granted in The United States. For more information about the patent please follow it on Espacenet.

For more detail information on the development of the project and there scientific and medical use please contact IOCB-TTO via email.