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<h4>DUVIRAGEL™</h4>
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<p class="spec">(antiherpeticum)</p>
<p>Active against fever blisters. It was manufactured by the Spofa company in the Czech Republic.</p>
<p>The Institute has established a long-term cooperation with the American biopharmaceutical company, Gilead Sciences, which deals with research, development and distribution of novel pharmaceuticals. The Institute and the company established a joint research center on July 13, 2006. The long-term collaboration based on the research of Prof. Antonín Holý has led to the development of a set of antiviral drugs, which are briefly listed below.</p>
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<h4>VISTIDE™</h4>
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<p class="spec">(cidofovir injection)</p>
<p>Treats opportunistic diseases accompanying AIDS (gastric ulcers, herpes zoster, smallpox, viral inflammation of the eyes, etc.).</p>
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<h4>VIREAD™</h4>
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<p class="spec">(tenofovir disoproxil fumarate)</p>
<p>An antiviral drug for AIDS treatment which helps block reverse transcriptase – a special protein that is needed for HIV to replicate. By interfering with the replication process, Viread as part of combination therapy helps lower the viral load. The active compound is tenofovir. This drug has been also approved for use in HBV infections.</p>
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<h4>HEPSERA™</h4>
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<p class="spec">(adefovir dipivoxil)</p>
<p>Active against hepatitis type B. It is based on adefovir and has practically no side effects.</p>
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<h4>TRUVADA™</h4>
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<p class="spec">(emtricitabine and tenofovir disoproxil fumarate)</p>
<p>For use in combination with other HIV medications to treat HIV infections in adults. Truvada combines two HIV medications, Emtriva (emtricitabine) and Viread (tenofovir), into one pill, which is taken once a day. It replaces 13 other tablets.</p>
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<h4>ATRIPLA™</h4>
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<p class="spec">(efavirenz, emtricitabine and tenofovir disoproxil fumarate)</p>
<p>The first-ever once-daily single tablet regimen for HIV intended as a stand-alone therapy. The product combines Sustiva (efavirenz) and Truvada (emtricitabine and tenofovir). It replaces the vast number of pills that patients formerly had to take.</p>
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